Speaker: Florian Schüeder, Ph.D.

Postdoctoral Fellow,
Department of Cell Biology
Yale University

Title: Development of smart DNA probes for multiplexed super-resolution microscopy

Abstract: Fluorescence microscopy, an important and widely used tool in biological research, has witnessed a true renaissance since the invention of methods circumventing the so-called diffraction limit, namely super-resolution techniques. In resonance with these advancements, my work combines advanced high-resolution microscopy with novel approaches from the field of DNA Nanotechnology to push the limits of light microscopy and apply it to cell-biological research. In this presentation, I will describe current advances of DNA-based super-resolution microscopy regarding novel immuno-labeling strategies, proximity detection, spatial imaging range (from close to the coverslip to whole cells and potentially tissues), image acquisition speed and spectrally unlimited multiplexed imaging.

Speaker Bio: Florian Schüeder studied Physics at the Ludwig-Maximilians University of Munich and the Wyss Institute of Harvard University from 2009 - 2015. Afterward, he pursued a Ph.D. in Biophysics at the Max Planck Institute of Biochemistry in Martinsried from 2015-2020. Since 2021 he is a Postdoctoral Fellow in the group of Joerg Bewersdorf at the Department of Cell Biology at Yale University.

Host: Kevin Dean, Ph.D.