"Dynamic Local and Systemic Antibody Responses to Mycobacterium Tuberculosis Infection"

Speaker:

Joshua Miles, B.S.
Graduate Student Researcher
Lenette Lu Lab
Division of Infectious Diseases & Geographic Medicine
UT Southwestern Medical Center

About Joshua Miles:

A native of Oregon, Mr. Miles earned his bachelor’s degree in biochemistry from George Fox University in Newberg, becoming the first college graduate in his family. As a research assistant, he studied lipoprotein metabolism and atherosclerosis with Dr. Sergio Fazio at Oregon Health and Science University. In 2020, he joined the Lu Lab, where he studies how diabetes uses antibody-mediated processes to alter the body’s ability to control tuberculosis, in both human and murine systems.

"Dissecting Antibody Responses to Mycobacterium Tuberculosis Virulence"

Speaker:

Lenette Lu, M.D., Ph.D.
Assistant Professor of Internal Medicine
Division of Infectious Diseases & Geographic Medicine
UT Southwestern Medical Center

About Lenette Lu:

Originally from China, Dr. Lu holds a bachelor’s degree in biology and Asian studies from Swarthmore College in Pennsylvania, where she graduated with high honors. She earned her medical degree and her doctoral degree in molecular virology at Case Western Reserve University School of Medicine in Cleveland. She completed an internal medicine residency at New York-Presbyterian/Weill Cornell Medical Center and a clinical fellowship in infectious diseases at Massachusetts General Hospital and Brigham and Women’s Hospital in Boston. She completed a postdoctoral research fellowship at Harvard School of Public Health and the Ragon Institute of Mass General, MIT, and Harvard.

Dr. Lu’s research focuses on how antibodies interface with the host microbe in infectious diseases. Her studies focus on Mycobacterium tuberculosis (Mtb), the bacterium that infects one out of four people worldwide and causes tuberculosis. Her goal is to increase understanding of the immune response to infection and, ultimately, to translate observations from humans to models of disease to further inform and direct human studies that could direct diagnostic, therapeutic, and vaccine development.