"Sub-Cellular and Spatiotemporal Re-Localization of Alpha-Synuclein to Mitochondrial Compartments Following IFN-β Innate Immune Activation in Primary Mouse Neurons"

Speaker:

Jayasri Das Sarma, Ph.D.
Professor of Biological Sciences
Indian Institute of Science Education and Research
Adjunct Associate Professor of Ophthalmology
University of Pennsylvania
Adjunct Professor, Centre for Molecular Neurosciences
Kasturba Medical College
Visiting Senior Researcher,Beckham Laboratory
Division of Infectious Diseases and Geographic Medicine
UT Southwestern Medical Center

About Jayasri Das Sarma:

An internationally recognized researcher in neurovirology and neuroimmunology, her work focuses on murine coronavirus-induced neuroinflammation, demyelination, and chronic progressive myelin loss, which mirror pathological features of human neurological disorders such as multiple sclerosis. Her research also explores cervical and ovarian cancers, with a broader interest in understanding disease mechanisms and developing new therapeutic approaches.

As a visiting senior researcher in the Beckham Laboratory, Dr. Das Sarma contributes expertise in neurovirology and coronavirus-induced neuroinflammation that complements the lab's focus on viral pathogenesis and neuroimmune responses. Her research seeks to understand how viral infections trigger immune-mediated damage in the central nervous system, with implications for multiple sclerosis and other neurological disorders.