"Moving Beyond the Tip of the Iceberg: Emerging Concepts in Tuberculosis Infection and Disease"

The Arthur Grollman Visiting Professorship in Experimental Medicine

Speaker:

Sarah Fortune, M.D.
Professor & Chair
Immunology & Infectious Diseases
Harvard T.H. Chan School of Public Health
 

About Sarah Fortune:

Originally from Lexington, Kentucky, Dr. Fortune holds a bachelor's degree in biology from Yale University. She earned her medical degree from Columbia and completed internal medicine residency training at Brigham and Women's Hospital, where she also obtained advanced training through a clinical fellowship in infectious diseases. She joined the Harvard faculty in 2006.

Dr. Fortune's research focuses on the molecular basis of population heterogeneity in Mycobacterium tuberculosis (Mtb) and the extent to which differences between mycobacterial cells contribute to differences in disease and treatment outcomes. Her lab combines bacterial genetic approaches with high throughput methodologies including population genomics, ssRNAseq and quantitative live cell imaging to define the molecular mechanisms by which Mtb generates diversity and how this diversity enables the bacterium to survive subsequent selective forces including antibiotics and immune selection. She is investigating the impact of host immune responses on the interaction of Mtb with the infected host, again working at both single cell and genomic levels.

In 2019, Dr. Fortune received a contract award to help establish three new Immune Mechanisms of Protection Against Mycobacterium tuberculosis (IMPAc-TB) Centers.