"Mapping the Metabolome"

Co-sponsored by Internal Medicine Research and the Office of Physician-Scientist Development

Speaker:

Thomas Mathews, Ph.D.
Assistant Professor, Children's Research Institute (CRI)
Assistant Director, CRI Metabolomics Shared Facility
UT Southwestern Medical Center

About Thomas Mathews:

Dr. Mathews holds a bachelor's degree in biochemistry from the University of Virginia, where he also earned his doctorate in bio-organic chemistry. Following his thesis work, Dr. Mathews pursued postdoctoral fellowships at The Scripps Research Institute and Vanderbilt University Medical Center, where he studied lipid metabolism and lipid signaling networks. In 2014, Dr. Mathews was awarded a fellowship through Oak Ridge National Laboratory to develop new tests for environmental and industrial toxins at the Centers for Disease Control and Prevention. After completing his fellowship at CDC, Dr. Mathews joined the faculty in the Children's Medical Center Research Institute at UT Southwestern and a senior research scientist in the Morrison Laboratory.

As Assistant Director of the CRI Metabolomics Facility, Dr. Mathews uses mass spectrometry to perform untargeted metabolomics, metabolite quantification, lipidomics, and stable isotope tracing. Together, these approaches provide a comprehensive picture of how metabolic networks drive disease pathogenicity, maintain tissue function, or signal transduction between cells.